Twenty plants identified and selected from Southwest and Middle belt Nigerian antimalarial ethnopharmacology were evaluated for in vitro cytotoxicity using the brine shrimp lethality assay. Alkaloids are large group of basic organic substances of natural origin usually plant which contain certain, hydrogen and one or more nitrogen atom. Phytother Res Aug 7;32 8: Haematological, biochemical and organ changes in broiler chickens fed varying levels of Morinda lucida brimstone leaf meal supplementation in the diets. The solvent fraction in test tubes A and B were moistened with 5 mL of water, while that in test tube C was left dry.

The plant was identified by taxonomists at the Botany Department University of Ghana who identified the correct species. Twelve of these plants, Alchornea cordifolia, Afromomum albo violaceum, Annona senegalensis, Cymbopogon densiflorus, Bridelia ferruginea, Ceiba pentandra, Morinda lucida, Hymenocardia acida, Coleus kilimandcharis, Dacryodes edulis, Caloncoba welwithsii, and Vinga unguiculata exhibited significant activities, thus, supporting the claims of the traditional healers and suggesting a possible correlation between the chemical composition of these plants and their uses in traditional medicine. Click here to sign up. Phytochemical screening and antimicrobial study on the leaves of Morinda lucida Rubiaceae. Department of Botany, University of Ghana, P. A total of nine components were isolated from the crude leaf extract. Plant identification and authentication has earlier been done.

Bearing in mind the fact that identifying and isolating the effective extract fractions and isolating active fractions of a crude extract may prove better therapeutically and probably less toxic than its crude form, the present study aims to evaluate the antihyperglycaemic profile of the solvent fractions of the ethanolic leaf extract of Morinda lucida Benth in normal and alloxan diabetic rats for 14 days.

In the concentration range of 0. Pharmacological evaluation of oral litdrature and antidiabetic effects of fresh leaves ethanol extract of Morinda lucida benth.


It can be naturally occurring chemical compounds containing basic nitrogen atoms Finar I. J Ethnopharmacol Jul 25; 3: The organic layer was collected into a reagent bottle and 4g of MgSO4 was added to absorb any traces of water present in the organic layer. Significant effects were observed with the four plants on T.


After twelve hours, it was filtered using a sintered glass filter and the filtrate lucuda collected in a round bottom flask and was concentrated using a rotary evaporator. Allergy and Immunology The effect of each extract fraction on the blood glucose concentration was then determined on the 15th day after an overnight fasting of the treated rats. The author wishes to acknowledge the technical assistance llterature Mr.

New chemotherapy has been eagerly awaited due liteeature severe side effects and the drug resistance issues plaguing current drugs. Antimicrob Agents Chemother 06 23;60 6: Such oxygen free compounds physically are usually volatile and liquids. Nat Prod Commun Oct;6 Three pieces of freshly prepared sodium picrate paper were inserted into the mouth of each tube and stoppered. Comparative toxicity of alloxan, N-alkyl-alloxans and ninhydrin to isolated pancreatic islets in vitro.

Epub May 7. However, further FR 5 2 Green 0. It will also help reviwe to know if any of their constituents will be extracted and used in other sphere of human endeavour like the chemical industries, cosmetics, specialty food and insecticidal industries.

The research work is important because it will help to know the alkaloidal content of llterature medicinal plant Morinda lucida leaves.

Structured questionnaires were used to explore the ethnobotanical practices amongst the traditional healers. The basicity of alkaloids depends on the lone pairs of electrons on their nitrogen atom thus forming salts with mineral acid such as HCl and H 2 SO 4 and organic acids such as tartatric acid or malic acid.

Evaluation of herbal antimalarial MAMA decoction-amodiaquine combination in murine malaria model.


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These substances can be used for therapeutic purposes and have been applied for several decades to serve as precursors for the synthesis of new drugs Evans, The crude ethanolic extract of the leaves is said to contain alkaloids, cardenolides and saponins Adomi and Umukoro, Further studies geared towards isolating and characterizing the antihyperglycaemic and antihyperlipidaemic loterature in MLE c will be required in the nearest future.

Juss Meliaceae leaves, plus four new variants of this combination were subjected to three in vivo antimalarial test models using chloroquine-sensitive Plasmodium berghei berghei to determine the most active under each of the test models. Department of Botany, University of Ghana, P.

Other coloured precipitate eeview orange and pale orange was gotten as a result of different solvents used for isolation. Artemisin, a product from medicinal plant indigenous to China, based on active principle of Artemisia annua, has been introduced into the Nigerian market. Phyto chemical analysis of MLE b showed the presence of flavonoids, alkaloids, tannin and saponin while MLE c showed the presence of flavonoids, alkaloids and anthraquinones.

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The addition of spots more of hexane and less of ethyl FR 1 Green 0. Compound A may be identified as chlorophyll due to its characteristic green colour and high yield.

literature review on morinda lucida

Plant identification and authentication has earlier been done. The presence of saponins, tannins, alkaloids, flavonoids, anthraquinones, glycosides and reducing sugars were determined by the simple and standard qualitative and quantitative methods described by Trease and Evans 13 and Sofowora

literature review on morinda lucida